Resources / Improving PD-L1 quality control using a dynamic rangecell line and Qualitopix analysis
Qualitopix®
Improving PD-L1 quality control using a dynamic range cell line and Qualitopix analysis
Originally presented at ECP 2023
Background

Immunohistochemistry (IHC) with PD-L1 is in use to predict ICI response in NSCLC patients. Inter-observer, inter- and intra-laboratory variability is, however, a known issue. In predictive IHC and to a lesser extent in panel based prognostic IHC, quality assurance principles and methods are becoming more relevant for optimal scoring. To improve scoring of PD-L1, artificial intelligence (AI) might be the way forward. Before AI can be used for daily practice, however, laboratories need to make sure that their IHC is a consistent assay instead of a routine stain.

Authors and institutions

Nils ‘t Hart1, Lars Gal1, Morten Grønning Nielsen2 and Mateusz Tylicki2

  1. Isala, Zwolle, The Netherlands
  2. Visiopharm, Hørsholm, Denmark
Questions? We’re here to help.
Contact us
Success
Your message has been successfully sent!