Resources / Dissecting the myeloid compartment of the tumor microenvironment with SignalStar™ multipleximmunohistochemistry and Phenoplex image analysis
Phenoplex™
Dissecting the myeloid compartment of the tumor microenvironment with SignalStarTM multiplex immunohistochemistry and Phenoplex image analysis
Originally presented at SITC 2024
Description
Myeloid cells, including macrophages, dendritic cells, monocytes, and granulocytes, are integral to the tumor microenvironment (TME). Recent multiomic technologies have identified distinct subpopulations of myeloid cells that regulate tumor progression and metastasis. Spatial biology technologies, such as multiplex immunohistochemistry (mIHC), are essential for investigating myeloid cell phenotype and function within the TME.
Authors and institutions
Sarah R Klein1, Lily Vu1, James Mansfield2, Fabian Schneider2
- Cell Signaling Technology, Inc., Danvers MA, USA
- Visiopharm A/S, Horsholm, Denmark
