The poster presents the development of chromogenic multiplex immunohistochemistry (mIHC) assays designed for clinical use. It highlights how multicolored chromogenic staining enables simultaneous profiling of multiple biomarkers in a single tissue sample, improving diagnostic accuracy and turnaround times. The work focuses on creating clinically relevant panels for lung cancer subtyping, immune engagement, and poorly differentiated malignancies, aiming to bridge the gap between research tools and routine clinical workflows for next-generation biomarker testing.

Natasha Reid^1,2*, Leah Officer-Jones², John Le Quesne^1,2,3

1. University of Glasgow
2. Cancer Research UK Scotland Institute
3. Department of Histopathology, QEUH