Metastasis Detection, AI Metastasis Detection, AI

Process APP

Revert

#90159

CE-IVD

Metastasis Detection, AI

Certified under IVDR

AI/deep learning-assisted metastasis detection in Lymph nodes – simplifying lymph node assessment.

Metastases in the lymph nodes are a significant indicator of cancer progression, which makes detection critical for treatment decisions. For lymph node assessment pathologists must review many slides per patient which amounts to a significant workload.

Visiopharm has developed a CE IVD certified AI deep learning application that has been trained to detect metastases in H&E stained lymph nodes associated with breast and colorectal adenocarcinoma.

This highly accurate APP enables pathologists to not only detect areas of metastases in lymph nodes. It also measures and orders metastases based on relevant features for either breast or colorectal cancer metastasis (largest metastasis diameter or total area of metastasis).

Verified with clinical samples, the Metastasis Detection APP improves a tedious workflow, and results in improved sensitivity and specificity of metastasis detection in lymph nodes from colorectal and breast adenocarcinoma.

Faster, cheaper, more sensitive

UMC Utrecht (The Netherlands) is using our Metastasis APP in daily diagnostic routine, fully integrated into their Sectra system. They have performed a clinical trial proving, that they not only increased sensitivity of metastasis detection, but also saved significant time (35%) and money (through IHC savings: 3000€/16 weeks) using our APP.

Read the paper

In EU/UK: CE IVD – for use in diagnostic procedures

Figure 1

Figure 1

The APP analyses H&E stained whole slide images of lymph nodes associated with breast or colorectal cancer with no need for manual interaction.

Figure 2

Figure 2

Metastases are identified as High Probability (red), Medium Probability (orange), Low Probability (yellow), allowing quick review for the pathologist.

Figure 3

Figure 3

The largest metastasis is measured for diameter (breast cancer) or area (colorectal cancer) respectively.

Figure 4

Figure 4

The APP is optimized for maximum sensitivity, so you can save time reviewing the slides with findings first.

Details

Benefits from AI-assisted Metastasis detection in your diagnosis workflow

  • Multi-indication:
    Verified on breast and colorectal data from 3 clinical sites for CE IVD certification
  • Improved results:
    Increased detection sensitivity compared to manual methods
  • Efficient:
    Automated slide sorting based on indication specific output

Summary of clinical performance results

Workflow

Visiopharm’s Metastasis Detection APP for whole slide images can easily be integrated into your workflow to become a potential time saver in your review process.

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