Outlined germinal centers (blue) on TMA core.
#10163
IHC, Germinal Center Detection
Developed for outlining germinal centers in tonsils, this Quickstart APP can be used to speed analysis. Tonsil tissue may be used as positive/negative controls for PD-L1 staining. Because the PD-L1 expression varies significantly between the tissue compartments, it is of interest to differentiate between tissue regions before evaluating the PD-L1 expression. This APP automatically outlines germinal centers in tonsils stained for PD-L1 and is intended as an accessory APP to help isolate regions for further analysis.
Outlined germinal centers (blue) on TMA core.
Details
Quantitative Output variables
Germinal Center Area [mm²]
Workflow
After loading your image, perform the following steps:
Step 1: Select the “10163 IHC, Germinal Cancer Detection.”
Step 2: Click “Run APP.”
Additional information
To run the APP, a NVIDIA GPU with minimum 4 GB RAM is required.
